Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 2.452


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1



Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_109729176 4.545 NM_023016
ANKRD57
ankyrin repeat domain 57
chr2_+_176842368 4.446 NM_006554
MTX2
metaxin 2
chr3_+_180348818 4.319 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr2_+_27659396 3.990 NM_032434
ZNF512
zinc finger protein 512
chr2_+_64605049 3.660 AFTPH
aftiphilin
chr7_+_107997527 3.597 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr7_+_107997544 3.563 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr9_+_113433364 3.441 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr2_+_64604940 3.367 NM_001002243
NM_017657
NM_203437
AFTPH


aftiphilin


chr7_-_107997132 3.268 NM_182529
NM_001130475
THAP5

THAP domain containing 5

chr7_+_107171809 2.900 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr1_+_36169260 2.765 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chr9_+_114288899 2.763 NM_133465
KIAA1958
KIAA1958
chr20_+_56659693 2.762 NM_001001433
NM_001134772
NM_001134773
NM_003763
STX16



syntaxin 16



chr3_+_133861894 2.734 UBA5
ubiquitin-like modifier activating enzyme 5
chr2_+_74007495 2.709 DGUOK
deoxyguanosine kinase
chr9_+_114289178 2.668 KIAA1958
KIAA1958
chr2_+_74007523 2.658 DGUOK
deoxyguanosine kinase
chr2_+_74007439 2.638 NM_080916
NM_080918
DGUOK

deoxyguanosine kinase

chr5_+_72830029 2.532 BTF3
basic transcription factor 3
chr20_+_33750645 2.516 NM_080748
ROMO1
reactive oxygen species modulator 1
chr4_+_119825983 2.473 NM_020961
METTL14
methyltransferase like 14
chr2_-_109728693 2.464 SEPT10
septin 10
chr20_-_33750457 2.421 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr2_-_109728958 2.400 NM_144710
NM_178584
SEPT10

septin 10

chr20_+_60395515 2.386 NM_001024
RPS21
ribosomal protein S21
chr5_+_36912656 2.385 NIPBL
Nipped-B homolog (Drosophila)
chr14_+_75688042 2.363 C14orf118
chromosome 14 open reading frame 118
chr7_+_86619805 2.328 NM_021145
DMTF1
cyclin D binding myb-like transcription factor 1
chr5_+_72830003 2.322 NM_001037637
NM_001207
BTF3

basic transcription factor 3

chr13_+_30089829 2.307 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr20_-_49008445 2.243 NM_003859
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr3_+_133861820 2.238 NM_024818
UBA5
ubiquitin-like modifier activating enzyme 5
chr13_-_30089509 2.230 HMGB1
high-mobility group box 1
chr1_+_181708068 2.223 NM_001174061
NM_173156
NM_201568
NM_201569
SMG7



Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)



chr1_+_181708235 2.214 SMG7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr14_+_75688025 2.194 C14orf118
chromosome 14 open reading frame 118
chr14_+_75687997 2.181 NM_017926
NM_017972
C14orf118

chromosome 14 open reading frame 118

chr10_-_43212681 2.179 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr15_+_21361901 2.162 MKRN3
makorin ring finger protein 3
chr2_+_187162969 2.147 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr10_+_97879645 2.142 ZNF518A
zinc finger protein 518A
chr14_+_34521945 2.140 SRP54
signal recognition particle 54kDa
chr2_+_69974581 2.137 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr1_+_212520899 2.108 NM_020197
SMYD2
SET and MYND domain containing 2
chr6_+_169844213 2.089 C6orf120
chromosome 6 open reading frame 120
chr6_+_169844161 2.085 NM_001029863
C6orf120
chromosome 6 open reading frame 120
chr22_+_20350272 2.084 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr6_+_169844186 2.083 C6orf120
chromosome 6 open reading frame 120
chr2_+_118288724 2.079 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_+_9379706 2.070 NM_001114092
NM_015453
THUMPD3

THUMP domain containing 3

chr20_+_49008754 2.059 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr2_+_118288754 2.058 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_+_52296893 2.054 GLYCTK
glycerate kinase
chr5_+_36912595 2.054 NM_015384
NM_133433
NIPBL

Nipped-B homolog (Drosophila)

chr16_+_21926939 2.052 NM_001164579
C16orf52
chromosome 16 open reading frame 52
chr2_+_118562499 2.033 NM_016133
INSIG2
insulin induced gene 2
chr2_+_118288753 2.028 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_-_74915722 2.026


chr7_+_86619580 2.024 NM_001142326
NM_001142327
DMTF1

cyclin D binding myb-like transcription factor 1

chr2_+_32244406 2.020 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr9_-_32991518 2.012 NM_001195249
NM_001195254
NM_001195248
NM_001195250
NM_001195251
NM_001195252
NM_175069
NM_175073
APTX







aprataxin







chr7_+_6583560 2.004 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr10_-_18988172 2.002


chr3_+_52296875 1.978 NM_001144951
NM_145262
GLYCTK

glycerate kinase

chr20_+_48560327 1.976 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr2_+_239000395 1.973 ASB1
ankyrin repeat and SOCS box containing 1
chr5_-_36912487 1.973 LOC646719
hypothetical LOC646719
chr20_+_42947754 1.970 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr20_+_48560326 1.959 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr2_+_46779827 1.953 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr6_-_7334940 1.952 NM_001170692
NM_001170693
NM_205864
CAGE1


cancer antigen 1


chr16_+_68353738 1.933 NM_007014
NM_199423
WWP2

WW domain containing E3 ubiquitin protein ligase 2

chr1_-_118273701 1.929 GDAP2
ganglioside induced differentiation associated protein 2
chr20_+_60395623 1.919 RPS21
ribosomal protein S21
chr15_+_56850681 1.907 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr20_+_48560315 1.906 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr1_-_52272020 1.902 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr3_-_15443985 1.899 NM_152396
METTL6
methyltransferase like 6
chr14_+_34521854 1.885 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr15_+_56850776 1.884 FAM63B
family with sequence similarity 63, member B
chr11_+_43337042 1.883 TTC17
tetratricopeptide repeat domain 17
chr6_-_169844023 1.877 NM_182552
WDR27
WD repeat domain 27
chr6_+_169844128 1.877 C6orf120
chromosome 6 open reading frame 120
chr5_+_138705416 1.871 NM_016480
PAIP2
poly(A) binding protein interacting protein 2
chr2_+_187163232 1.865 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr20_+_48560264 1.862 NM_002827
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr20_+_42947764 1.854 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr4_+_110956085 1.853 NM_018983
NM_032993
GAR1

GAR1 ribonucleoprotein homolog (yeast)

chr12_+_68150332 1.843 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr7_-_30600868 1.835 LOC285949
hypothetical protein LOC285949
chr20_+_16658608 1.817 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr1_-_181708022 1.815 LOC284649
hypothetical LOC284649
chr7_+_39572396 1.812 NM_020192
C7orf36
chromosome 7 open reading frame 36
chr20_+_43028533 1.808 NM_006282
STK4
serine/threonine kinase 4
chr8_+_11179724 1.797 MTMR9
myotubularin related protein 9
chr6_+_160068553 1.790 WTAP
Wilms tumor 1 associated protein
chr5_+_148705169 1.787 NM_152407
GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr5_+_69732561 1.784 SMA4
glucuronidase, beta pseudogene
chr1_+_118273887 1.781 NM_006784
WDR3
WD repeat domain 3
chr7_+_99451110 1.780 NM_003439
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr6_+_160068544 1.769 WTAP
Wilms tumor 1 associated protein
chr6_+_160068531 1.761 WTAP
Wilms tumor 1 associated protein
chr20_+_43028590 1.760 STK4
serine/threonine kinase 4
chr11_-_117628211 1.756 NM_198275
MPZL3
myelin protein zero-like 3
chr21_+_36614347 1.755 NM_015358
MORC3
MORC family CW-type zinc finger 3
chr1_+_196392513 1.751 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr16_+_55777739 1.750 NM_133368
RSPRY1
ring finger and SPRY domain containing 1
chr5_+_138705445 1.744 PAIP2
poly(A) binding protein interacting protein 2
chr17_+_42355482 1.743 NM_001012511
NM_004287
NM_054022
GOSR2


golgi SNAP receptor complex member 2


chr1_+_93584088 1.740 DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr5_+_147743734 1.735 NM_030793
NM_205836
FBXO38

F-box protein 38

chr1_+_52380633 1.732 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr2_+_65308332 1.723 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr7_+_107171514 1.721 NM_024814
CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr2_+_218790143 1.721 ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr4_-_101086891 1.719 NM_001031723
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr5_+_65258316 1.712 ERBB2IP
erbb2 interacting protein
chr2_+_3362449 1.709 NM_016030
TTC15
tetratricopeptide repeat domain 15
chr6_+_170457774 1.709 FAM120B
family with sequence similarity 120B
chr1_+_93584078 1.706 DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr15_-_81216179 1.706


chr10_-_43212703 1.704 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_+_93584051 1.703 DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr14_+_68935172 1.703 SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr6_+_160068598 1.703 NM_152857
WTAP
Wilms tumor 1 associated protein
chr2_+_46779553 1.700 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr16_+_82399132 1.695 HSBP1
heat shock factor binding protein 1
chr6_+_7535404 1.693 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr10_+_18988282 1.690 NM_178815
ARL5B
ADP-ribosylation factor-like 5B
chr16_+_82399073 1.688 NM_001537
HSBP1
heat shock factor binding protein 1
chr13_+_44937025 1.685 NM_031431
COG3
component of oligomeric golgi complex 3
chr11_+_10729357 1.677 NM_014633
CTR9
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_118273869 1.676 WDR3
WD repeat domain 3
chr5_-_74098641 1.668 NM_032380
NM_170681
NM_170691
GFM2


G elongation factor, mitochondrial 2


chr1_+_93584064 1.668 NM_001938
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr3_-_133861182 1.661 NM_032169
ACAD11
acyl-CoA dehydrogenase family, member 11
chr1_-_93583910 1.660 LOC100131564
hypothetical LOC100131564
chr17_+_42355492 1.658 GOSR2
golgi SNAP receptor complex member 2
chr3_+_102763369 1.656 NM_017819
RG9MTD1
RNA (guanine-9-) methyltransferase domain containing 1
chr4_+_109761170 1.653 NM_000995
NM_033625
RPL34

ribosomal protein L34

chr2_+_48395271 1.647 NM_002158
FOXN2
forkhead box N2
chr7_+_30600926 1.637 GARS
glycyl-tRNA synthetase
chr14_+_89792646 1.637 NM_002802
PSMC1
proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr2_+_128565222 1.634 NM_020120
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_239000306 1.632 NM_001040445
ASB1
ankyrin repeat and SOCS box containing 1
chr15_+_63948823 1.624 NM_004663
RAB11A
RAB11A, member RAS oncogene family
chr20_+_42537927 1.623 NM_001039199
NM_024331
TTPAL

tocopherol (alpha) transfer protein-like

chr14_+_68935133 1.621 NM_018375
SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr7_+_27746335 1.614 TAX1BP1
Tax1 (human T-cell leukemia virus type I) binding protein 1
chr10_-_43212166 1.611 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr4_-_101086754 1.607 DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr2_+_218790109 1.606 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr20_+_48560354 1.600 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr12_+_49080858 1.594 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr16_+_68353662 1.593 WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr5_+_147743753 1.591 FBXO38
F-box protein 38
chr6_+_4721640 1.587 NM_004824
CDYL
chromodomain protein, Y-like
chr2_-_65308220 1.583 LOC729324
hCG1986447
chr13_+_78953495 1.577 NDFIP2
Nedd4 family interacting protein 2
chr11_+_8660913 1.573 RPL27A
ribosomal protein L27a
chr1_+_22224571 1.571 HSPC157
hypothetical LOC29092
chr2_+_178685396 1.571 NM_152945
RBM45
RNA binding motif protein 45
chr3_+_15444056 1.559 NM_033083
EAF1
ELL associated factor 1
chr16_+_8799170 1.553 NM_000303
PMM2
phosphomannomutase 2
chr6_+_170705345 1.546 NM_001172085
NM_003194
TBP

TATA box binding protein

chr13_+_25726755 1.526 NM_001260
CDK8
cyclin-dependent kinase 8
chr16_+_29994797 1.523 PPP4C
protein phosphatase 4, catalytic subunit
chr5_+_138705469 1.521 PAIP2
poly(A) binding protein interacting protein 2
chr4_+_79916576 1.521 BMP2K
BMP2 inducible kinase
chr22_+_39817733 1.520 EP300
E1A binding protein p300
chr15_+_41450568 1.520 NM_014444
TUBGCP4
tubulin, gamma complex associated protein 4
chr12_+_99185289 1.514 SCYL2
SCY1-like 2 (S. cerevisiae)
chr6_+_126349327 1.500 TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr12_+_99184977 1.498 SCYL2
SCY1-like 2 (S. cerevisiae)
chr20_+_19945930 1.494 NM_016100
NM_181528
NAA20

N(alpha)-acetyltransferase 20, NatB catalytic subunit

chr11_+_123997968 1.492 TBRG1
transforming growth factor beta regulator 1
chr14_+_68934855 1.478 SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr3_+_133861425 1.473 UBA5
ubiquitin-like modifier activating enzyme 5
chr11_+_123997983 1.470 TBRG1
transforming growth factor beta regulator 1
chr20_+_60246982 1.468 OSBPL2
oxysterol binding protein-like 2
chr18_+_31963851 1.457 ELP2
elongation protein 2 homolog (S. cerevisiae)
chr16_+_29994818 1.456 PPP4C
protein phosphatase 4, catalytic subunit
chr13_+_37821964 1.454 UFM1
ubiquitin-fold modifier 1
chr10_-_51293220 1.448 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr11_-_6459139 1.447 NM_012402
ARFIP2
ADP-ribosylation factor interacting protein 2
chr5_+_110455768 1.443 NM_139281
WDR36
WD repeat domain 36
chr16_+_24648446 1.439 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr14_+_56805358 1.439 NM_018229
MUDENG
MU-2/AP1M2 domain containing, death-inducing
chr20_+_60246972 1.438 NM_014835
NM_144498
OSBPL2

oxysterol binding protein-like 2

chr4_+_110956360 1.434 GAR1
GAR1 ribonucleoprotein homolog (yeast)
chr20_-_5041482 1.430 NM_001009923
NM_001009924
NM_001009925
NM_014145
C20orf30



chromosome 20 open reading frame 30



chr18_+_31963879 1.425 NM_018255
ELP2
elongation protein 2 homolog (S. cerevisiae)
chr11_+_123997980 1.424 TBRG1
transforming growth factor beta regulator 1
chr16_-_8798973 1.415 NM_015421
TMEM186
transmembrane protein 186
chr6_+_7335011 1.413 NM_031480
RIOK1
RIO kinase 1 (yeast)
chr17_+_70520339 1.410 NM_001545
ICT1
immature colon carcinoma transcript 1
chr6_+_126349268 1.409 NM_001031712
TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr7_-_16651885 1.409 NM_020319
ANKMY2
ankyrin repeat and MYND domain containing 2
chr12_+_99185334 1.408 NM_017988
SCYL2
SCY1-like 2 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 1.94e-39 GO:0044260 cellular macromolecule metabolic process
1.31 8.89e-30 GO:0043170 macromolecule metabolic process
1.25 2.22e-28 GO:0044237 cellular metabolic process
1.39 1.15e-21 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 3.97e-21 GO:0090304 nucleic acid metabolic process
1.47 1.18e-19 GO:0010467 gene expression
1.19 2.17e-19 GO:0008152 metabolic process
1.39 5.12e-19 GO:0044267 cellular protein metabolic process
1.20 5.18e-18 GO:0044238 primary metabolic process
1.47 5.98e-18 GO:0016070 RNA metabolic process
1.30 1.55e-14 GO:0034641 cellular nitrogen compound metabolic process
1.42 4.09e-14 GO:0009059 macromolecule biosynthetic process
1.43 5.38e-14 GO:0034645 cellular macromolecule biosynthetic process
1.32 9.54e-14 GO:0071841 cellular component organization or biogenesis at cellular level
1.28 6.21e-13 GO:0006807 nitrogen compound metabolic process
1.76 6.39e-13 GO:0016071 mRNA metabolic process
1.68 1.73e-12 GO:0006396 RNA processing
1.31 3.38e-12 GO:0071842 cellular component organization at cellular level
1.26 3.65e-12 GO:0071840 cellular component organization or biogenesis
1.84 8.36e-12 GO:0016032 viral reproduction
1.85 3.46e-11 GO:0006397 mRNA processing
1.27 3.66e-11 GO:0019538 protein metabolic process
1.09 6.54e-11 GO:0009987 cellular process
1.57 8.95e-11 GO:0046907 intracellular transport
1.38 1.38e-10 GO:0006996 organelle organization
1.64 1.96e-10 GO:0009057 macromolecule catabolic process
1.25 2.02e-10 GO:0016043 cellular component organization
1.90 1.27e-09 GO:0008380 RNA splicing
1.51 1.39e-09 GO:0045184 establishment of protein localization
1.67 1.67e-09 GO:0044265 cellular macromolecule catabolic process
1.52 1.73e-09 GO:0015031 protein transport
2.08 4.50e-09 GO:0000375 RNA splicing, via transesterification reactions
1.28 1.05e-08 GO:0044249 cellular biosynthetic process
1.44 1.47e-08 GO:0008104 protein localization
1.27 1.98e-08 GO:0009058 biosynthetic process
2.06 2.13e-08 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.06 2.13e-08 GO:0000398 nuclear mRNA splicing, via spliceosome
1.75 1.03e-07 GO:0030163 protein catabolic process
1.75 4.30e-07 GO:0044257 cellular protein catabolic process
1.21 4.43e-07 GO:0060255 regulation of macromolecule metabolic process
1.75 5.50e-07 GO:0051603 proteolysis involved in cellular protein catabolic process
1.59 9.23e-07 GO:0006974 response to DNA damage stimulus
1.76 1.14e-06 GO:0006412 translation
1.75 1.27e-06 GO:0006511 ubiquitin-dependent protein catabolic process
1.35 1.84e-06 GO:0033036 macromolecule localization
1.29 2.20e-06 GO:0006464 protein modification process
1.73 2.22e-06 GO:0019941 modification-dependent protein catabolic process
1.78 2.64e-06 GO:0032446 protein modification by small protein conjugation
1.37 2.66e-06 GO:0044248 cellular catabolic process
1.71 2.95e-06 GO:0070647 protein modification by small protein conjugation or removal
1.72 3.45e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.39 5.12e-06 GO:0007049 cell cycle
1.23 7.18e-06 GO:0010468 regulation of gene expression
1.55 7.85e-06 GO:0070727 cellular macromolecule localization
1.55 8.95e-06 GO:0034613 cellular protein localization
1.27 9.41e-06 GO:0043412 macromolecule modification
1.63 9.58e-06 GO:0006886 intracellular protein transport
1.78 1.24e-05 GO:0016567 protein ubiquitination
1.31 1.53e-05 GO:0009056 catabolic process
1.42 2.12e-05 GO:0033554 cellular response to stress
1.50 3.24e-05 GO:0000278 mitotic cell cycle
1.33 3.28e-05 GO:0051641 cellular localization
1.17 4.99e-05 GO:0019222 regulation of metabolic process
1.37 5.58e-05 GO:0032774 RNA biosynthetic process
1.40 9.24e-05 GO:0022402 cell cycle process
2.02 9.33e-05 GO:0048193 Golgi vesicle transport
1.34 9.77e-05 GO:0051649 establishment of localization in cell
1.44 1.12e-04 GO:0022403 cell cycle phase
1.70 1.15e-04 GO:0010608 posttranscriptional regulation of gene expression
2.38 1.28e-04 GO:0006353 transcription termination, DNA-dependent
1.42 1.34e-04 GO:0016192 vesicle-mediated transport
1.61 1.80e-04 GO:0051301 cell division
1.17 1.91e-04 GO:0031323 regulation of cellular metabolic process
1.76 5.48e-04 GO:0033365 protein localization to organelle
1.21 6.90e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.76 6.98e-04 GO:0071843 cellular component biogenesis at cellular level
1.16 6.98e-04 GO:0080090 regulation of primary metabolic process
1.42 1.18e-03 GO:0051726 regulation of cell cycle
2.31 1.70e-03 GO:0072594 establishment of protein localization to organelle
1.75 1.80e-03 GO:0022613 ribonucleoprotein complex biogenesis
1.47 1.81e-03 GO:0034621 cellular macromolecular complex subunit organization
1.35 2.69e-03 GO:0043933 macromolecular complex subunit organization
1.19 2.93e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.59 2.95e-03 GO:0048285 organelle fission
1.29 3.16e-03 GO:0044085 cellular component biogenesis
1.81 3.24e-03 GO:0006417 regulation of translation
1.33 5.26e-03 GO:0008219 cell death
2.60 6.57e-03 GO:0006369 termination of RNA polymerase II transcription
1.79 6.68e-03 GO:0010498 proteasomal protein catabolic process
1.79 6.68e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.68 7.06e-03 GO:0000075 cell cycle checkpoint
1.33 7.80e-03 GO:0016265 death
1.66 8.20e-03 GO:0071156 regulation of cell cycle arrest
2.15 8.32e-03 GO:0031123 RNA 3'-end processing
1.40 9.32e-03 GO:0006259 DNA metabolic process
2.08 1.62e-02 GO:0022618 ribonucleoprotein complex assembly
1.55 1.70e-02 GO:0000087 M phase of mitotic cell cycle
1.67 1.77e-02 GO:0006457 protein folding
1.17 1.86e-02 GO:0031326 regulation of cellular biosynthetic process
1.31 2.08e-02 GO:0006351 transcription, DNA-dependent
1.50 2.24e-02 GO:0010564 regulation of cell cycle process
1.38 2.36e-02 GO:0071822 protein complex subunit organization
1.17 2.40e-02 GO:0009889 regulation of biosynthetic process
1.65 2.63e-02 GO:0006605 protein targeting
1.34 2.67e-02 GO:0006915 apoptosis
1.62 2.80e-02 GO:0048011 nerve growth factor receptor signaling pathway
2.01 2.92e-02 GO:0071826 ribonucleoprotein complex subunit organization
1.54 2.94e-02 GO:0000280 nuclear division
1.54 2.94e-02 GO:0007067 mitosis
1.34 3.19e-02 GO:0012501 programmed cell death
1.43 3.40e-02 GO:0016044 cellular membrane organization
1.73 3.44e-02 GO:0022415 viral reproductive process
1.92 3.74e-02 GO:0006414 translational elongation
1.43 3.80e-02 GO:0000279 M phase
1.42 4.39e-02 GO:0061024 membrane organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.17e-56 GO:0005622 intracellular
1.18 1.53e-56 GO:0044424 intracellular part
1.23 5.94e-48 GO:0043231 intracellular membrane-bounded organelle
1.23 1.73e-47 GO:0043227 membrane-bounded organelle
1.20 2.07e-45 GO:0043229 intracellular organelle
1.20 1.30e-44 GO:0043226 organelle
1.30 4.02e-35 GO:0005634 nucleus
1.26 3.29e-27 GO:0044446 intracellular organelle part
1.25 6.99e-26 GO:0044422 organelle part
1.18 1.09e-24 GO:0005737 cytoplasm
1.45 1.22e-23 GO:0044428 nuclear part
1.41 2.91e-21 GO:0031974 membrane-enclosed lumen
1.41 8.91e-21 GO:0070013 intracellular organelle lumen
1.40 3.05e-20 GO:0043233 organelle lumen
1.45 5.56e-19 GO:0031981 nuclear lumen
1.20 1.90e-17 GO:0044444 cytoplasmic part
1.82 4.49e-16 GO:0030529 ribonucleoprotein complex
1.26 9.25e-14 GO:0032991 macromolecular complex
1.43 3.15e-12 GO:0005654 nucleoplasm
1.25 1.83e-09 GO:0043228 non-membrane-bounded organelle
1.25 1.83e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.30 2.90e-09 GO:0005829 cytosol
2.25 7.85e-09 GO:0005681 spliceosomal complex
1.04 5.06e-06 GO:0005623 cell
1.04 6.63e-06 GO:0044464 cell part
1.52 8.59e-06 GO:0005730 nucleolus
1.23 1.40e-05 GO:0031090 organelle membrane
2.35 1.47e-05 GO:0071013 catalytic step 2 spliceosome
1.19 3.68e-05 GO:0043234 protein complex
1.40 6.79e-05 GO:0044451 nucleoplasm part
1.28 1.43e-04 GO:0005739 mitochondrion
1.37 4.83e-04 GO:0031967 organelle envelope
1.74 6.16e-04 GO:0005840 ribosome
1.66 7.79e-04 GO:0016604 nuclear body
1.91 8.29e-04 GO:0016607 nuclear speck
1.35 1.73e-03 GO:0031975 envelope
1.60 2.58e-03 GO:0005635 nuclear envelope
1.75 3.72e-03 GO:0044445 cytosolic part
1.37 9.01e-03 GO:0005694 chromosome
1.73 1.06e-02 GO:0031965 nuclear membrane
2.03 1.31e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.34 2.23e-02 GO:0044431 Golgi apparatus part
2.61 2.48e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.37 2.73e-02 GO:0000139 Golgi membrane
1.20 2.78e-02 GO:0012505 endomembrane system
1.91 4.06e-02 GO:0000790 nuclear chromatin
1.87 4.34e-02 GO:0042470 melanosome
1.87 4.34e-02 GO:0048770 pigment granule

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 3.98e-21 GO:0005515 protein binding
1.10 7.79e-18 GO:0005488 binding
1.30 5.29e-17 GO:0003676 nucleic acid binding
1.60 6.33e-14 GO:0003723 RNA binding
1.23 8.11e-06 GO:0000166 nucleotide binding
1.24 1.30e-05 GO:0008270 zinc ion binding
1.25 2.50e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.24 3.57e-05 GO:0017076 purine nucleotide binding
1.24 6.14e-05 GO:0032553 ribonucleotide binding
1.24 6.14e-05 GO:0032555 purine ribonucleotide binding
1.82 2.62e-04 GO:0008168 methyltransferase activity
1.25 5.47e-04 GO:0005524 ATP binding
1.24 7.58e-04 GO:0030554 adenyl nucleotide binding
1.25 7.91e-04 GO:0032559 adenyl ribonucleotide binding
1.12 8.41e-04 GO:0003824 catalytic activity
1.77 8.89e-04 GO:0016741 transferase activity, transferring one-carbon groups
1.66 1.72e-03 GO:0003713 transcription coactivator activity
1.18 3.71e-03 GO:0003677 DNA binding
1.77 5.30e-03 GO:0003735 structural constituent of ribosome
1.18 5.66e-03 GO:0046914 transition metal ion binding
1.32 7.97e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.90 8.29e-03 GO:0008026 ATP-dependent helicase activity
1.90 8.29e-03 GO:0070035 purine NTP-dependent helicase activity
1.31 1.05e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.45 1.09e-02 GO:0003712 transcription cofactor activity
1.45 1.25e-02 GO:0000988 protein binding transcription factor activity
1.45 1.25e-02 GO:0000989 transcription factor binding transcription factor activity
1.31 1.31e-02 GO:0016462 pyrophosphatase activity
1.97 1.48e-02 GO:0008565 protein transporter activity
1.30 2.32e-02 GO:0017111 nucleoside-triphosphatase activity
1.51 3.79e-02 GO:0016881 acid-amino acid ligase activity
1.19 4.39e-02 GO:0016740 transferase activity
1.94 4.83e-02 GO:0008135 translation factor activity, nucleic acid binding